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Delicious Cattle Drive Casserole with beef, veggies, and cheese served in a rustic dish

Cattle Drive Casserole

A skillet-sizzled dinner with a warm biscuit crust, Cattle Drive Casserole is comfort food that comes together quickly and feeds a crowd.
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Prep Time 20 minutes
Cook Time 30 minutes
Total Time 50 minutes
Servings: 8 servings
Course: Dinner, Main Course
Cuisine: American
Calories: 350
Ingredients Method Notes

Ingredients
  

Meat & Vegetables
  • 1.5 pounds Lean Ground Beef Choose 85–90% lean for good flavor.
  • 1 piece Red Bell Pepper, seeded, chopped
  • 1 piece Yellow Onion, chopped
  • 1 ounce Taco Seasoning Mix
Biscuit Base
  • 2.5 cups Biscuit Mix (like Bisquick) Forms the base and acts like a quick bread crust.
  • 1 cup Water
  • 1 can Cooking Spray, like Pam For greasing the casserole dish.
Creamy Layer
  • 0.5 cups Sour Cream
  • 0.5 cups Mayonnaise
  • 4 ounces Diced Green Chiles, drained
  • 1.5 cups Cheddar Cheese, Fiesta Blend, shredded, divided Use freshly shredded for best melt.
  • 1 teaspoon Garlic Powder
Topping
  • 0.5 cups Salsa, mild Dollops over the sour cream layer.

Method
 

Preparation
  1. Preheat the oven to 350°F.
  2. Cook the ground beef in the skillet over medium-high heat until brown.
  3. In a mixing bowl, combine biscuit mix with water until a uniform dough forms.
Cooking
  1. Add chopped vegetables to the cooked beef, sauté for about 4 minutes.
  2. Spread the beef mixture over the biscuit base in the casserole dish.
  3. Mix sour cream, mayonnaise, green chiles, cheese, and garlic powder and spread over the beef layer.
  4. Top with tablespoons of salsa and sprinkle remaining cheese.
  5. Bake for 30 minutes until hot and bubbly.
Finishing Touches
  1. Let the casserole rest for 5–10 minutes before serving.

Notes

This casserole is great for potlucks, can be made ahead and frozen. Adjust spices according to taste.